Deletion of IL‐6 enhances renal microvascular autoregulatory responses and responses to purinoceptor activation
نویسندگان
چکیده
منابع مشابه
Direct assessment of renal microvascular responses to P2-purinoceptor agonists.
Studies were performed to determine the responsiveness of rat juxtamedullary afferent arterioles to receptor-selective P2-purinoceptor agonists. Experiments were performed in vitro using the blood perfused juxtamedullary nephron technique, combined with videomicroscopy. Renal perfusion pressure was set at 110 mmHg and held constant. Basal afferent arteriolar diameter averaged 22.0 ± 0.6 μm ( n ...
متن کاملpragmatic transfer in compliment responses and chastisements by iranian learners of english
فرهنگ های گوناگون دریافت ها و تعبیر های مختلفی از تناسب و ادب دارند. بنابراین، ارتباط میان فرهنگی خطرات ذاتی خطای ارتباطی را نشان می دهد. این پژوهش به منظور تعیین وقوع انتقال منظورشناختی زبان در زبان بینابینی زبان آموزان ایرانی، اختلاف منظورشناختی زبان را بین فارسی و انگلیسی در کنش های کلامی پاسخ تحسین و انتقاد بررسی می کند.داده ها از میان 33 آمریکایی انگلیسی زبان، 85 زبان آموز ایرانی در سطوح م...
15 صفحه اولGene deletion of Gabarap enhances Nlrp3 inflammasome-dependent inflammatory responses.
The γ-aminobutyric acid A receptor-associated protein (Gabarap) functions in γ-aminobutyric acid A receptor trafficking and postsynaptic localization in neurons, but its physiological roles in other systems have not been studied. In this study, we report that Gabarap-deficient mice are more susceptible to mortality in two sepsis models. An underlying mechanism of this higher mortality rate in G...
متن کاملMalnutrition enhances cardiovascular responses to chemoreflex activation in awake rats.
Several studies in the literature suggest that low-protein intake is associated with increases in sympathetic efferent activity and cardiovascular disease. Among the possible mechanisms, changes in the neurotransmission of cardiovascular reflexes have been implicated. Therefore, the present study comprised the evaluation of chemoreflex responsiveness in rats subjected to a low-protein diet duri...
متن کاملPhysiological role for P2X1 receptors in renal microvascular autoregulatory behavior.
This study tests the hypothesis that P2X1 receptors mediate pressure-induced afferent arteriolar autoregulatory responses. Afferent arterioles from rats and P2X1 KO mice were examined using the juxtamedullary nephron technique. Arteriolar diameter was measured in response to step increases in renal perfusion pressure (RPP). Autoregulatory adjustments in diameter were measured before and during ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.4.a762-a